Upgrade to Patient Pro Medical Professional? I am at 15 MG per weekI take 5 mg on M/W/F and my body is getting used to it but I have passed the two year mark and no signs of it abating. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. Do not use methimazole in larger or smaller amounts or for longer than recommended. Sounds like your doctor wants to work with you though if he gave you that choice. Press J to jump to the feed. If you don't feel better after taking your medication for several months, you may need a dose adjustment or a different medicationnot a complete stop of your regimen. Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): Change in taste. DID YOU NOTICE ANXIETY OR RAPID HEARTBEAT OR COULD I BE ANXIOUS ABOUT GETTING OFF THE MEDICATION. People with Hashi's are extremely sensitive to both the thyroid-blocking meds and the thyroid hormone replacement meds. Cold intolerance is a typical hypo symptom, but I've always had periods of heat intolerance as well and I've not been hyper in the past 12 yrs. Can You Eat Soy If You Have a Thyroid Condition? What Do Herpes Sores Look Like at Different Stages. Should I stop Methimazole over a high TSH? Thyroid storm. My Endocrinologist has started weaning me off of Methimazole. My levels are all in good range so Im confused why she wants to see if I can lower the dose. Debilitating fatigue; tiredness; pressure in head - related, Diagnosed with Graves' disease - my symptoms are high pulse, loose stools and very tired, Graves Disease - Hyperthyroid does anyone have the same symptoms. My methimazole was 5 mg once a day. I should have listened to him. In the case of our patient above, both laboratory parameters and the overall clinical picture confirm our suspicion of thyroid storm. And other symptoms of hypothyroidism. So hopefully youre getting bloodwork again soon to make sure things are ok? Thank God for my good health again. To me, it really is the missed mimic of several disease states, as described above in our possibly uroseptic patient. I have hyper numbers - very low TSH and high/normal T4 and I have the same kind of symptoms you have: freezing cold and sometimes achy legs. I don't believe our bodies respond well to abrupt changes. Methimazole can pass into breast milk and may harm a nursing baby. Solomon B, Wartofsky L, Burman K. Adjunctive cholestyramine therapy for thyrotoxicosis. ACMT Toxicology Visual Pearl: Swollen Lips, PECARN Pediatric Head Trauma: Official Visual Decision Aid, A Starters Roadmap to EM Resources: Books, Websites, and Apps, D50 vs D10 for Severe Hypoglycemia in the Emergency Department, The Dirty Epi Drip: IV Epinephrine When You Need It, Tips for Interpreting the CSF Opening Pressure, Trick of the Trade: Mix Ceftriaxone IM with Lidocaine for Less Pain, Trick of the Trade: Urine Pregnancy Test Without Urine, Wellness and Resiliency during Residency: EM is a career with unresolved stories, Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License, Academic Life in Emergency Medicine - All Rights Reserved (except for the PV Cards and MEdIC Series PDFs), Block the production and release of thyroid hormone (preventing the opposing team from getting the ball and scoring), Block the sympathetic outflow (preventing the soccer ball from going out of bounds), Block peripheral conversion of T4 to T3 (preventing penalty kicks), Mechanism of action: Inhibit thyroid peroxidase, an enzyme involved in the production of T3 and T4 through the iodination of tyrosine residues on thyroglobulin, Agents: propylthiouriacil (PTU) and methimazole (MMI), No head-to-head trials have shown any benefit of using one thionamide over another in the management of thyroid storm. If you have lived with untreated thyroid disease for years, you may have gotten used to living with symptoms. Management of severe thyrotoxicosis when the gastrointestinal tract is compromised. If you need surgery, tell the surgeon ahead of time that you are using methimazole. Endometriosis And Thyroid disease: Is There Really A Connection? It interferes with the step that causes the iodination of tyrosine residues in thyroglobulin, mediated by the enzyme thyroid peroxidase, thus preventing the synthesis of thyroxine (T4) and triiodothyronine (T3). unable to get any financial help*SSI/DISABILITY DENIED X4, ***this post is edited by moderator *** *** private e-mails not allowed*** Please read our Terms of Use. Levels of hormone can swing up quickly. Two-step method for administration: Test dose: 0.5 to 1 mg as slow IV push administered over 10 minutes Subsequent doses: 1 to 3 mg IV over 10 to 15 minutes every few hours to desired effect with monitoring of cardiac rhythm Esmolol can be considered as an alternative agent Use of the forums is subject to our Terms of Use My current doctor, who is new to me, also wanted to wean me off but she tested my antibodies first. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. But don't tapper too much and too fast. I also wanted to know my Carnitine levels before I started taking it so I asked my doc to give me a requisition to get it tested and found I was deficient. 2. PMID: 24176474. Initial dose: Mild hyperthyroidism: 15 mg orally per day. yes. It can take a few days to a few weeks for you to even start noticing a difference in how you feel. Take your doses at regular intervals to keep a steady amount of the drug in your body at all times. .50 was the low normal range. But it can also cause weight loss and a reduced need for sleep, which some people actually welcome. Found that I could not take vitamin D pills, that they had to be the gel caps. You may report side effects to FDA at 1-800-FDA-1088. Are you losing weight? Before Tom died, I felt amazingly well off the armor even with low TSH. I was tested again today my gp ordered that I do will have results later today. over a year ago. Herpes spreads by oral, vaginal and anal sex. Why would she try to wean me off the medicine if my numbers didnt indicate remission? yellow eyes or skin. If you are not taking your thyroid medication because of one or more of the following reasons, try the suggested solutions to address your concerns. I got pulled over for speeding on Christmas eve last year. We offer this Site AS IS and without any warranties. Overdose symptoms may include nausea, vomiting, upset stomach, headache, joint pain, fever, itching, swelling, or pale skin and easy bruising or bleeding. If true allergy to iodine or contraindication to iodine therapy (e.g. Methimazole is an antithyroid medicine. Takiing Armour (thyroid hormone replacement) has seemed to cause your hyperthyroidism. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. When I go back in May, he will probably wean down to 25 mg a week. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Slowly weaning off or tapering to the right dose is the best method. Hodak S, Huang C, Clarke D, Burman K, Jonklaas J, Janicic-Kharic N. Intravenous methimazole in the treatment of refractory hyperthyroidism. If someone else had been through this I'd certainly like to know their opinion. Thanks. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. Now down to 5 mg a day, 6 days a week (so 30 mg a week). Is it possible that it is my thyroid or should I see my PCP for the attacks. I am a 52 year old female and I had been on 15MG Methimazole for the over 2 months and my Endo lower the dosage to 10MG (took the And I vote you find another endo even if you do even out - you want someone who knows their stuff to monitor you in case you relapse in the future. Nabil N, Miner D, Amatruda J. Methimazole: an alternative route of administration. They took blood work and X-rays, and this went on for over 4 hours. Gaitonde DY, Rowley K, Sweeney L. Hypothyroidism: An update. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. Each time I reduce, my TSH elevates- but my T3 stays within range which is what my endo focuses onand it does take about six weeks for my body to adjust to the lower dosebut it does adjust. They do better controlling their thyroid hormones using Regular L-Carnitine. This was very irresponsible of them and I was not able to be well enough to work for a year after that. I said ok, not thinking anything of it, but after halving my dose for a few weeks Ive started to feel bad again. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. I was on 5 mg daily and now my dr halved it to 2.5 daily. Stop using methimazole and call your doctor right away if you have signs of infection such as: What Happens When You Don't Take Your Thyroid Medication. Methimazole is used to treat hyperthyroidism, a condition that occurs when the thyroid gland produces too much thyroid hormone. Endocrine causes of dangerous Fever. Went back to 10mg, after 2 consecutive blood tests were good (12 weeks) and then went to 7.5, just did a another 12 week stint, all is good so went to 5 mg this week (very happy). why does this happen? IS THERE A WEIGHT LOSS PLAN THAT ADDRESSES THYROIDECTOMY - what do you do to lose weight? Yet many hypo sufferers complain of it as well. I read somewhere that ALA can work on TSH. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. I feel fine. Increased risk of infection. You should go off it slowly. Herpes spreads by oral, vaginal and anal sex. Didn't find the answer you were looking for? Methimazole is an antithyroid medicine. I'd love to be able to start these again once I'm diagnosed and under the care of a naturopath. The state patrol who should be serving and protecting, was searching to destroy based on my appearance bulging eyes, unable to hold head back and count due to goiter,and the yellowing eyes and tremors crawling skin causes jerking movements. We recommend using methimazole (MMI; 0.25 to 1.0 mg/kg per day). It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Create an account to follow your favorite communities and start taking part in conversations. Clearly, there are sensible health reasons to take your prescribed thyroid medication. When did you start going off it? Untreated Graves' disease caused severe problems for me. It bounced around .53 to .25 then .50 again but never above. She has a past medical history of hypertension and she has been compliant with her medications. My T3 and T4 are at mid to lower end of the range. Tell your doctor about all your current medicines and any you start or stop using, especially: a blood thinner--warfarin, Coumadin, Jantoven; or. Even while I was having a thyroid storm and my hr was way to high it took the doctor telling me I was going to die before I let him give me meds to slow my heart. I never was given clarity about what "the damage" entailed though:(. i teally feel I have late stage chronic lime. Helpful - 0 Comment leilajax Gimel is right, it only has a 6 hour half life. Now I am in none. While you may experience some symptoms of overactive thyroid more than others, and you may even consider some of them beneficial, it is important to be aware of the strain this condition is putting on your heart, bones, and overall health. I tried this and my TSH rose from less than 0.001 (where it had been for 2 years) to 0.12 (in the right direction but not enough). Generic name: methimazole [me-THIM-a-zole] Previous: "Why Wasn't I Taught This Stuff In Medical School?" There are 3 kinds of L Carnitine suppslements what kind did you take to help? You must tell us if you are pregnant, even if you My GP suggestd similar action as my TSH levels started rising (only just out of range)and my FT4 dropped. If the hyperthyroidism returns, the antithyroid drugs are re-started. It is also used before thyroid surgery or radioactive iodine treatment. Methimazole side effects. Special Populations We offer this Site AS IS and without any warranties. Reddit and its partners use cookies and similar technologies to provide you with a better experience. Dr. Fereidoun Azizi. ALiEM is not endorsed by, sponsored by, or affiliated with the University of California San Francisco or any institution. If you skip or stop your medicine entirely, you can experience a number of short-term and long-term consequences, including: Untreated hyperthyroidism can increase your risk of stroke or heart attack. Thyroid Problems: Extremes Are Never Good. I havent tried to wean off before. :), The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. I hadn't tested much in over a year- hoping this prior post link will work on this post to refresh anyone's memory who cares to 27M, 6'0, 174lb, Been on NP for about 4 months, Don't smoke or drink. You should not shock your body that way. I take individual vitamins and supps daily: B complex, C, D, LipoFlavinoid, potassium magnesium asparate, B2, CoQ10, (the last 3 for migraine) Flax capsules, Biotin. So I don't think there is one size fits all but I do believe you need the information from the tests your doc does as well as learning about your body and its symptoms and what works and what doesn't in order to get well. She is the author of "The Thyroid Diet Revolution.". By Mary Shomon I was taken to jail where I was geld for two weeks without my medicine and let me tell you I got sick with peripheral edema, vasculitis. Take the missed dose as soon as you remember. How Are Thyroid Disorders Linked To An Increased Risk Of Developing Osteoporosis? Thyroid medications usually do not work right away. Usual Pediatric Dose for Hyperthyroidism: Initial dose: 0.4 mg/kg orally per dayMaintenance dose: 0.2 mg/kg orally per day (approximately half the initial dose) Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervals. I have been told by every doctor that I've seen in the past few months that it is a serious med, and even though I was only on it for mere months it could have done damage. You will be able to stop your methimazole or PTU immediately. STIs are the most common cause of genital sores. manic bipolar unable to get along with others. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. Again, be sure to discuss any concerns with your doctor and do not stop taking your medication without consulting with them first. I started out at 30mg a day. I'm very upset because I figure he's the doctor and shouldn't have left that choice up to me. I have my test results and I am taking 15MG Methimazole a day since 5/25 and the Endo told me to continue taking the same dosage Me again. Why Your Thyroid Hormone Levels May Be Fluctuating, Medications Used to Treat Thyroid Disease, Hyperthyroidism vs. Hypothyroidism: Differences and Symptoms, Thyroid Disease Facts and Statistics: What You Need to Know, Guide to Dietary Supplements and Thyroid Disease. Written by Cerner Multum. I was taking a dosage of forty, then cut it down to twenty for about two weeks, and then was taken off of it entirely. Anterior cervical discectomy, no fusion - what to expect? A strategy of high MMI doses plus T4 was not used in these patients. The question is now . I have hyper numbers - very low TSH and high/normal T4 and I have the same kind of symptoms you have: freezing cold and sometimes achy legs. Some people have Graves alone, some have Hashi's alone and some people have both Graves and Hashi's at the same time. If you have thyroid disease and don't take your prescribed medications to manage it, you can have a number of serious long-term effects. It works by making it harder for the body to make thyroid hormone. If your regular doctor can't explain why you have this problem, it can be fixedcheck out naturopathic ways to treat symptoms, you are worth it. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Okay I didn't know you had completely stopped the Methimazole, but I think you misread what I wrote. However, there are a lot of side effects from taking it and stop taking it (especially, without tapering). Endocrinologic emergencies often fall at the wayside and are not generally considered as a possible diagnosis up front in patients in the emergency department who meet the criteria for systemic inflammatory response syndrome (SIRS). Tell your doctor at once if you develop signs of infection. She seems relatively anxious on physical exam, and you note that she is diaphoretic. All rights reserved. Mercado M, Mendoza-Zubieta V, Bautista-Osorio R, Espinoza-de los. Gimel is right, it only has a 6 hour half life. 0.84 t4 sounds pretty low so maybe that was part of the decision? I was on 10mg daily of Tapazole, went to 7.5 in the early winter but also returned to work at same time (bad idea). If you want to get notified by every reply to your post, please register. Some thyroid medications can also cause hair loss, which most people find frustrating and undesirable. Herpes sores blister, then burst, scab and heal. Was there any tapering of the dose at all? The problem can be changing your diet, as you don't know how the thyroid will react to this. Seemed like it got stuck or something. I have my test results and I am taking 15MG Methimazole a day since 5/25 and the Endo told me to continue taking the same dosage Hi, Birth defects an option due to untreated Graves' disease? As far as symptoms go, I have been gassy (for no reason), fatigued more than usual, depressed, short tempered,and I'm either too cold or too hot. One thing my Endo and I agree on is that he will not stop a patient's medication entirely unless their antibody levels are within the normal range even if all their thyroid labs are normal. Sometimes it can take a few months to adjust your medication, but the end result is well worth it. i have been taking 2.5 mg of methimazole every other day for the past 3 years which is 4x a week and now she told me to just take 2.5mg once a week for 6 weeks and then just stop. I'm not in hypo yet I don't think the doctors just think that I'm going into hypo..? It got to the point where I could barely eat. Radioiodine in the treatment of hyperthyroidism. It can also increase the risk of developing a dangerous condition known asthyroid storm, which has a high fatality rate. Dr.DanielleWeiss is the founder of the Center for Hormonal Health and Well-Being, a personalized, proactive, patient-centered medical practice with a unique focus on integrative endocrinology. https://patient.info/forums/discuss/stopping-methimazole-543742. Thanks, THANKS FOR YOUR HELP LET ME KNOW IF YOU THINK OF ANYTHING. What dose were you on to start with? and Privacy Policy and steps will be taken to remove posts identified You can keep your medicine in an obvious place, such as your bedroom or kitchen, or you can use a pill organizer to keep you on track. It should always be tapered incredibly gradually, there's always a small rebound period for me no matter how small I chop it with my pill cutter. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Anthing would be helpful. Treatment of hyperthyroidism with a combination of methimazole and cholestyramine. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Furthermore, you should fully understand the consequences of untreated thyroid disease. Diabetes Tests And Diagnosis: What To Expect During Your Medical And Physical Examinations? HI, I was diagnosed with Graves Disease last fall (2016). When your lab tests are like yours (low TSH and high Free T4) you are hyper. T3 total: 332; FT3 11.1; FT4 387, TSH <.005. Your healthcare provider will check your thyroid levels and adjust your dose as needed. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. If your levels start to drop toward the lower end of the scale, you'll be able to taper the dose down a bit - to 20 mg a day. Sowiski J, Junik R, Gembicki M. [Effectiveness of intravenous administration of methimazole in patients with thyroid crisis]. What Do Herpes Sores Look Like at Different Stages. We strive to reshape medical education and academia in their evolution beyond the traditional classroom. My pcp didn't like that. Not all possible interactions are listed in this medication guide. fatigue and hyperthyroidism and Graves' Disease. Follow all directions on your prescription label. Brand names: Tapazole, Northyx thanks for letting us know what you have gone through. Diagnosis of thyroid storm can be somewhat of a challenge because of this, but a scoring system developed by Burch and Wartofsky 1 can assist in determining the likelihood of thyroid storm in patients based on presenting signs and symptoms. unusual tiredness or weakness. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. The achy legs suggests you may be carnitine deficient, also vitamin D deficient and Magnesium deficient and these things are extremely important for thyroid patients. Not taking your medication also increases your risk of fatal conditions like myxedema coma if you are hypothyroid, and thyroid storm if you are hyperthyroid. If there is a contraindication for the use of methimazole, alternative methods to treat hyperthyroidism should be considered after discharge, such as radioactive iodine or surgery. Well, nothing like wasting money for an antiquated panel is there? How long were you on Methimazole before weaning off? The doctor told me to take a Metoprolol once in the morning, then, around lunch time, take the 20 mgLisinopril, then, at dinner time, take another Metoprolol. appropriate medical assistance immediately. Natural Solutions For Graves' Disease & Hashimoto's Thyroiditis. Methimazole prevents the thyroid gland from producing too much thyroid hormone. decreased sense of taste. Is there some other underlying issue that is taking place? It does not stay in the body for 2-3 weeks, this is just not true. Bartle W, Walker S, Silverberg J. Rectal absorption of propylthiouracil. For oral dosage form (tablets): For hyperthyroidism: AdultsAt first, 15 to 60 milligrams (mg) per day, given in 3 divided doses about every 8 hours. I did this (decided to lessen the dose) all by myself with a naturopath's advice (my "specialist" seems to have forgotten about me and never did the follow up in mid-March, and I am not disappointed =;) The biggest help has been to deal with my stress. tightness in the chest. Most people who have thyroid disease feel better with the appropriate medication. She enjoys giving lectures and writing articles for both the lay public and medical audiences. I told my endo. HELP. A list of national and international resources and hotlines to help connect you to needed health and medical services. Could the anxiety be stemming from you actually still needing the methimazole? You will learn what these results mean very quickly and you can always learn more about them online. Answer. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. A list of national and international resources and hotlines to help connect you to needed health and medical services. Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervals.
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