"Suramin in the treatment of AIDS: mechanism of action. And this gem of a video by Judy Mikovits. I believe people are so caught up in their own little bubble that they have no idea of what is going on in the real world. Suramin. Thus, reduction in extracellular pH facilitates P2X2 and P2X2/3 receptors but inhibits P2X1, P2X3, P2X4 and P2X7 receptors (. Dr. Naviaux no longer has any control over the next clinical studies or the priorities of different diseases for testing, although he is recommending ASD, ME/CFS, post-acute SARS-CoV-2 multi-system chronic fatigue syndrome, also called long-COVID, and post-treatment Lyme disease (PTLDS) as a few of the top candidates. All good gifts come from the Lord. What a super easy way to give my body Suramin on a regular basis. They do change our DNA in the sense that they take it back to how it was when we were a baby. 2) Blocks Il-6 activity and binding to Il-6 receptor in cancer cells, https://www.autismweb.com/forum/viewtopic.php?t=30356&start=20, http://joe.endocrinology-journals.org/content/202/1/141.full.PDF. These are proving to be beneficial for people who have taken the jab, or those who come in contain with injected people and find they are experiencing bad symptoms. The Eastern White Pine (. However, it is imperative to choose the right pine needles as there are 20 known toxic varieties of pine trees. The differences are about 20% higher. But raw milk just doesnt last as long in the fridge, so keep most of it in the freezer and only bring out one serving at a time into the fridge the night before using. 16.Spigelman, Zachary, Amy Dowers, Susan Kennedy, Dennis DiSorbo, Michael O'Brien, Ronald Barr, and Ronald McCaffrey. Tea made from pine cones is a real treasure of useful substances. Just a point of clarification. Suramin successfully improved all the core symptoms of ASD and the metabolic and GI abnormalities in both animal models and a small human clinical trial. i just emailed a well known ME/CFS doctor i know (who wishes to remain anonymous) with the names of the two herbs/supplements mentioned at the top of this thread, and he said: "I have talked with every prominent herbalist I know to see if there is a similar substance out there, and so far, nothing.". If interested look up her name and look for turpentine video. I wish I could. With this blockade the GDP will not release from the G subunit so it can not be replaced by a GTP and become activated. i'm not sure why i'm saying that med, but for some reason it came up in my research around suramin alternatives. (2017) conducted a trial that studied the impact of a single dose of suramin in children with autism and compared their result to a group of children who received the placebo drug (Saline). "Studies on antitumor effects of pine needles, Pinus densiflora Sieb. Quoting from our 2017 publication,Like many intravenous drugs, when administered improperly by untrained personnel, at the wrong dose and schedule, without careful measurement of drug levels and monitoring for toxicity, suramin can cause harm. Its such a dreadful thing that they robbed us of such good food and have destroyed it by pasteurizing and homogenising. We now have evidence of the injections containing: mRNA, spike protein, graphene oxide, and highly toxic SM-102, and other potentially toxic substances. . [8][9] It is considered first-line treatment for Trypanosoma brucei rhodesiense, and second-line treatment for early-stage Trypanosoma brucei gambiense, where pentamidine is recommended as first line. She was annoyed people were being told to make it. "Structural basis for repurposing a 100-years-old drug suramin for treating COVID-19." But of-course they would keep that completely secret and only use it for anyone of their own people who somehow was subjected to the j/a/b. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. It is not found in pine needles and cannot be found in any herbal teas. Intramuscular and subcutaneous administration could result in local tissue inflammation or necrosis[citation needed]. Each of the 19 different purinergic receptors have different functions, and new roles for specific P2Y, P2X and P1 receptors are still being discovered. current analyst for the pharmaceutical and medical device industries, **For the Full Spike Protein Protocol (including. The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivo. Further investigation of the herb reveals a study (Smith . In this trial, 10 male children with ASD were grouped into five pairs, ages 5-14 years. It loves the cold, the colder the better. Dr. Daniels has now been using this and has no issues and I have been using it also. Research is already being hurriedly done in that direction in the hope that many lives can be saved and much severe illness avoided. I believe that most of the fake foods will be removed and people will learn how to eat food they were designed to eat. You can obtain enough from pine needle tea (pine, spruce, cedar and fir) . You quoted Rheum Palmatum, but many other plants contain Emodin. POLG Mutations Associated with Alpers Syndrome and Mitochondrial DNA Depletion. Suramin is 20 or more times as powerful as remdesivir, which is the only currently approved anti-COVID-19 drug. C: Use with caution if benefits outweigh risks. Cat's Claw. Here he talks about suramin, which Dr Judy mentioned. Regarding our own experiment with natural antipurinergic therapy, we've been trialing Kudzu for the past three weeks and the outcome has been pretty impressive. or Best Offer. [16], Suramin was first made by the chemists Oskar Dressel, Richard Kothe and Bernhard Heymann at Bayer AG laboratories in Elberfeld, after research on a series of urea-like compounds. Medical Disclaimer: I am no longer a practicing medical professional, and I am not doctor. especially valuable as potential new sources for rapid responses against the ongoing 4! Suramin is used in the treatment of African sleeping sickness (African trypanosomiasis) and river blindness (onchocerciasis), infections caused by parasites. If you dont like something one way, do something else with it until it becomes acceptable. [11], The synthesis of suramin itself and structural analogs is by successive formation of the amide bonds from their corresponding amine (aniline) and carboxyl (as acyl chloride) components. No medical research confirms this yet, but people have been using suramin for autism and as a powerful antiviral. I tried it for the lipid modulating properties and have seen some improvement in various serum lipid ratios (though of course I don't know that this is specifically attributable to the Sytrinol). You must log in or register to reply here. SMALL SURAMIN STUDY. It's the first time we've been so close to having a drug that can potentially treat ASD symptoms. In summary, a lowered pHe enhanced the activity of all agonists at P2X2 receptors but, with the exception of suramin, not antagonists. We use cookies to ensure that we give you the best experience on our website. Suramin (as mentioned by Dr Judy Mikovits, PhD) and Shikimic acid are both found within the needles of the common pine tree. "Suramin" is the antidote to the bioweapons and transmission. Suramin further decreases the activities of a large number of enzymes involved in DNA and RNA synthesis and modification: DNA polymerases (103, 104), RNA polymerases (103, 105, 106), reverse transcriptase (18, 103), telomerase (67), and enzymes involved in winding/ unwinding of DNA (107, 108) are inhibited by suramin, as well as histone- and chromatin-modifying enzymes like chromobox proteins . You must realise too that the medbeds are for good and not evil. ME/CFS is a multi-systemic neurological disease, distinct from chronic fatigue as a symptom. "Antiproliferative effects of suramin on lymphoid cells. Thanks for being part of this journey with me. 15.Mooon, Jeong-jo, Young-bok Han, and Jin-suk Kim. Suramin is not extensively metabolized and about 80% is eliminated via the kidneys. . Suramin is manmade and is not a natural product found anywhere in Nature. National Library of Medicine. Boys with autism spectrum disorder who received 10 mg/kg of a suramin IV infusion known as PAX-101 experienced greater improvements in symptoms than those who received 20 mg/kg of the same . Its interesting whats going on first she says one thing and then another. interesting! The same protocol is very useful to protect those concerned with the spike protein transmission FROM those whove been injected. Give it a shake and there you have it, another nice bottle of Fennel water! The boys were extensively monitored in the following 6 weeks for suramin blood levels, a panel of blood chemistry, adverse effects and autism-related traits. They were ahead of their time back then. Journal of clinical oncology 10, no. The more stress, the more eATP is released. This has the effect of blocking downstream G protein mediated signaling of various GPCR proteins including rhodopsin, the A1 adenosine receptor, the D2 receptor,[19] the P2 receptor,[20][21] and ryanodine receptors. Reddit and its partners use cookies and similar technologies to provide you with a better experience. The research is promising and the findings are backed up by similar studies. You can inoculate the tiniest amount of Suramin and reverse Autism! Suramin is a secondary agent in treatment of Onchocerciasis (river blindness), but because of its toxicity, it is rarely used. (See protocol below). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143661/, https://news.ycombinator.com/item?id=14458230. [2], Suramin was made at least as early as 1916. Our bodies are built in such a way they can withstand being treated badly for a time, but it doesnt go on forever. and this shows what Graphene oxide does to the blood of the vaccinated under the microscope: This protocol may mitigate damage in those with buyers remorse whove been injected with spike protein, graphene oxide, SM-102, and mRNA. Studies on this have just recently started . This is the most important Antidote. UC San Diego Health, May 26, 2017, "Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy", "Low-dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial", "Q and A - Suramin and Autism | UC San Diego Health", "Suramin is an active site-directed, reversible, and tight-binding inhibitor of protein-tyrosine phosphatases", https://en.wikipedia.org/w/index.php?title=Suramin&oldid=1126333005, Antrypol, 309 Fourneau, Bayer 205, others, This page was last edited on 8 December 2022, at 20:02. Every time, before I drink, I give the bottle a good shake. Acta Biomater 84, 378-390. 12.Cheng, B., Gao, F., Maissy, E., and Xu, P. (2019). Kudzu is POSSIBLY SAFE for most people when taken by mouth appropriately for up to 4 months or when injected intravenously (by IV) for up to 20 days. The Trail from Suramin to Pine Needle Tea "Suramin provides an antidote for those affected by the spike protein "contagion". About 500-1000 mg of fish oil per day is recommended for children dealing with ADHD. 4. "Understanding the mechanism of the antimitogenic activity of suramin." Naviaux, R.K. & Nguyen, K.V. et Zucc." Click here. Turn your volume down inititially. Curcumin was the active ingredient in an intravenous infusion that killed the patient of a California-licensed naturopathic doctor. Myers, Charles, Michael Cooper, Cy Stein, Renato LaRocca, M. M. Walther, Gary Weiss, Peter Choyke, Nancy Dawson, Seth Steinberg, and Margaret M. Uhrich. I am a mother. Suramin | C51H40N6O23S6 | CID 5361 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Im worried about the mark of the evil one. B-complex vitamins: The "complex" part is important. Suramin does not cross the bloo Treatment of late-stage human African trypanosomiasis is complicated by the presence of trypanosomes within the central nervous system (CNS). We make no representations, nor any warranties, nor assume any liability for the content herein; nor do we endorse any particular product, provider, or service. Looks like part of my theories is debunkable - one of the authors did think to check IL-6 and IL-6R before and after exercise in CFS patients (good on him) and found no differences between them and the controls, although he did find "F(2)-isoprostanes were higher (P<0.05) in CFS patients at rest and this difference persisted immediately and 24 h post-exercise." Ive just stumbled upon upon your site and discovered suramin can be obtained naturally. Ha ha Jeff good point! Specifically, cat's claw works to supercharge your immune system, while simultaneously repairing damaged DNA and boosting your virus-fighting white blood cells ( 14 ). Journal of cellular physiology 132, no. It likes to be on the cold side of the mountain and doesnt do well on the warmer side. But it would be fine to do both. Suramin is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 M), and SirT5 (IC50=22 M). https://www.biorxiv.org/content/10.1101/2020.10.06.328336v1, 3. readily accessible. Is Rice Bran Oil an Authentic Health Food. http://www.fedup.com.au, Dr Judy explicitly says that pine needle tea will NOT act as anecdote, in fact, it can be toxic and has similar properties to terpentine. JavaScript is disabled. It is illegal to import suramin for human use without FDA approval. (3) This study also says suramin doesn't work well on p2x4. [5] It is on the World Health Organization's List of Essential Medicines. Once all the needles have sunk to the bottom and the tea has cooled, pour through a strainer into It is a symmetric molecule in the center of which lies a urea (NHCONH) functional group. No I am not sure if they need to be heated for the Suramin to be released. THE CONTENT ON THIS SITE IS PRESENTED IN SUMMARY FORM, IS GENERAL IN NATURE, AND IS PROVIDED FOR INFORMATIONAL PURPOSES ONLY; IT IS NOT ADVICE, NOR SHOULD IT BE TREATED AS SUCH. Yes, it can certainly be found naturally. We were lucky that suramin is a non-selective inhibitor of most of the known types of purinergic receptors. I was excited by these findings too esp as I am also on the autism spectrum. Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. I have others mentioned in this post: (This page contains a link to products for purchase. OK, last one, because I'm still trying to understand it. So head over today and like, share and download a few episodes! 2. Betsholtz, Christer, Ann Johnsson, Carl-Henrik Heldin, and Bengt Westermark. I think thats an old wives tale. "Antimicrobial activity of the essential oil of young pine shoots (Picea abies L.)." [10] Other skin reactions include skin rash, swelling and stinging sensation. Mayan's Secret Organic Black Cumin Seed Oil. This compound is known to inhibit the binding of growth factors (eg, epidermal growth factor [EGF], platelet-derived growth factor [PDGF], tumor growth factor-beta [TGF-beta]) to their receptors and thus antagonize the ability of these factors to stimulate growth of tumor . Some places sell powdered camel milk, but I do not think that is as good, and I dont recommend it. (137) $15.99 New. I have been taking Sytrinol, 150 mg x 2 daily, for well over 6 months. Zoltner, Martin, Gustavo D. Campagnaro, Gergana Taleva, Alana Burrell, Michela Cerone, Ka-Fai Leung, Fiona Achcar et al. "Suramin inhibition of growth factor receptor binding and mitogenicity in AKR2B cells." Cat's claw, hailing from a woody vine in the Amazon rainforest, is another herb with spectacular antiviral properties. I believe the White Pine is totally safe as well. Jacques Update:Facebook and social media platforms are cracking down on Conservative/holistic health content. Most importantly the mysterious seizure-like episode has disappeared. 2. The goal will be to find synergistic therapies that can bring patients with chronic conditions through the stages of healing discussed above. (2020). It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Thank you for pointing that out. 1! Suramin is a medication used to treat African sleeping sickness and river blindness. Antiviral research 7, no. Also, Suramin not only blocks P2X7 but also the related Pannexin 1 channel. Pine needle tea, wild-foraged in the USA, picked from northern white pines | Protects against infection, strengthens immunity, high in antioxidants, natural suramin (20 Count (Pack of 1)) BALANCE PICK Natural Pine Needle Tea Powder - Product of Korea - (3.52oz (100g)) Ethanol was found to decrease the time-constant of deactivation of ATP-gated ion channels without affecting the time-constant of activation, indicating that ethanol inhibits the function of these receptors by an allosteric decrease in the affinity of the agonist binding site. It would be interesting to know if I can get raw camel milk in Australia at least in the powdered form. This document does not contain all possible interactions. Naviaux Lab, 2023. Now, a new study reviews the potential for curcumin, a natural alkaloid derived from turmeric, and nanosystems to treat COVID-19. The Journal of clinical investigation 90, no. [11], Less common side effects include extreme fatigue, ulcers in the mouth, and painful tender glands in the neck, armpits and groin. (especially on purinergic signaling.) Suramin is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 M). https://buff.ly/3KmTZZd, I am only on FB now by the grace of God. LifeWave X39 and X49 Performance Bundle - 30 Patch. 3 (1985): 265-273. Other rare systemic effects include decreased blood pressure, fever, rapid heart rate, and convulsions. Ethanol has been found to inhibit ATP-gated ion channel function [aka p2x family afai] by shifting the agonist concentration-response curve to the right in a parallel manner, increasing the EC50 without affecting Emax of this curve. Are there any supplements or lifestyle factors we can utilize to emulate the effects that suramin has? The most effective dosage solution is the Pine Needle Tincture. ", 15.Mooon, Jeong-jo, Young-bok Han, and Jin-suk Kim. God always has the answer! I dont know but I do know that God will provide. the inhibitory effects of NhPV and Suramin were confirmed by the wild type SARS-CoV-2 (hCoV-19 . Some of the other P2X7 and P2Y2 inhibiting compounds listed at the bottom of. We strongly caution against the unauthorized use of suramin.1Homeopathic use of suramin is also illegal and untested. northwestern Africa and North America, is known . Suramin contains six aromatic systems four benzene rings, sandwiched by a pair of naphthalene moieties plus four amide functional groups (in addition to the urea) and six sulfonic acid groups. The Neem's active substance, azadirachtin, 51 a tetranortriterpenoid plant limonoid, is a potent insect feeding deterrent and, if consumed, 52 causes . antiviral activities [24], and most of these are generally of low toxicity, cheap and 2! I'm fascinated and excited by this new research on cell danger response (CDR): Low-dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial abstract and the ramifications for autism as well as anxiety and other chronic health conditions. It happened with the first a few days and soon I realized he started to sleep very well without Melatonin. 19. A lawn treated with Roundup would also have no grass, as well as no dandelions, no anything. ! When given as a medication, it is usually delivered as the sodium sulfonate salt as this formulation is water-soluble, though it does deteriorate rapidly in air. The best kind would be to get actual frozen raw camel milk. Rooibos Tea has become our all-time favourite tea now. We are covering everything from vaccines, parenting topics, alternative medicine, and I just gave my testimony of past abortion. Stresses of all kinds are translated by the cell into graded eATP release. Wormwood is one of the most effective antiparasitic herbs in the world, and one of the best natural alternatives to Ivermectin. The active ingredients in wormwood are toxic to most types of intestinal worms, including Giardia lamblia, a parasite responsible for giardiasis. The synthesis of suramin was an extension of Paul Ehrlichs pioneering work that showed that certain chemical dyes were concentrated in microbial parasites like the trypanosomes that cause African sleeping sickness. Suramin can be found in trees, plants and spices which may be growing even in your front lawn! [4] Common side effects include nausea, vomiting, diarrhea, headache, skin tingling, and weakness. An extremely good read Fed Up by Sue Dengate. You must log in or register to reply here. Due to its anti-inflammatory properties, turmericspecifically curcumin, the main active ingredientmay be one of the top natural remedies showing promise for treatment and management of autism symptoms. [7], Suramin is used for treatment of human sleeping sickness caused by trypanosomes. [2] Sore palms of the hands and soles of the feet, trouble seeing, fever, and abdominal pain may also occur. Salgado-Benvindo, C. et al. Suramin does not distribute well into cerebral spinal fluid and its concentration in the tissues is equivalently lower than its concentration in the plasma.
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